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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TH
All Species:
6.67
Human Site:
S125
Identified Species:
11.28
UniProt:
P07101
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P07101
NP_000351.2
528
58600
S125
S
P
R
A
T
K
P
S
A
L
S
R
A
V
K
Chimpanzee
Pan troglodytes
XP_508221
618
67613
S215
S
P
R
A
T
K
P
S
A
L
S
R
A
V
K
Rhesus Macaque
Macaca mulatta
Q2HZ26
490
56076
S99
V
H
I
E
S
R
K
S
R
R
R
S
S
E
V
Dog
Lupus familis
XP_855547
495
55650
T103
R
A
V
K
A
F
E
T
F
E
A
Q
I
H
H
Cat
Felis silvestris
Mouse
Mus musculus
P24529
498
55975
K102
S
S
L
S
R
A
L
K
V
F
E
T
F
E
A
Rat
Rattus norvegicus
P04177
498
55948
K102
S
S
L
S
R
A
V
K
V
F
E
T
F
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507458
568
65241
G162
F
S
L
K
E
E
V
G
A
L
A
K
V
L
C
Chicken
Gallus gallus
P70080
445
51121
K54
H
I
E
S
R
K
S
K
R
R
N
S
E
F
E
Frog
Xenopus laevis
Q92142
481
55388
K89
L
I
H
I
E
S
R
K
S
K
R
R
N
S
E
Zebra Danio
Brachydanio rerio
NP_571224
489
55584
F98
T
L
K
V
F
E
T
F
E
A
K
I
H
H
L
Tiger Blowfish
Takifugu rubipres
NP_001027874
476
54285
A85
K
I
F
E
T
F
D
A
K
L
L
H
I
E
S
Fruit Fly
Dros. melanogaster
P18459
579
65977
G173
K
E
G
I
S
S
L
G
R
I
L
K
A
I
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P90925
457
52111
K66
H
I
E
S
R
P
S
K
T
H
E
G
C
Y
E
Sea Urchin
Strong. purpuratus
XP_786206
522
59629
G119
S
K
E
D
M
G
F
G
S
L
S
E
A
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.1
43.1
84.2
N.A.
83.3
84.2
N.A.
45
43.7
42.9
65.1
51.8
43.1
N.A.
40.7
46.7
Protein Similarity:
100
83.6
60
87.5
N.A.
86.9
87.8
N.A.
60.3
58.7
60.2
77.6
66.8
61.4
N.A.
59.2
65.7
P-Site Identity:
100
100
6.6
0
N.A.
6.6
6.6
N.A.
13.3
6.6
6.6
0
13.3
6.6
N.A.
0
26.6
P-Site Similarity:
100
100
26.6
20
N.A.
13.3
13.3
N.A.
40
26.6
20
20
20
40
N.A.
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
15
8
15
0
8
22
8
15
0
29
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
0
8
22
15
15
15
8
0
8
8
22
8
8
29
29
% E
% Phe:
8
0
8
0
8
15
8
8
8
15
0
0
15
8
0
% F
% Gly:
0
0
8
0
0
8
0
22
0
0
0
8
0
0
0
% G
% His:
15
8
8
0
0
0
0
0
0
8
0
8
8
15
8
% H
% Ile:
0
29
8
15
0
0
0
0
0
8
0
8
15
8
0
% I
% Lys:
15
8
8
15
0
22
8
36
8
8
8
15
0
0
15
% K
% Leu:
8
8
22
0
0
0
15
0
0
36
15
0
0
15
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% N
% Pro:
0
15
0
0
0
8
15
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
8
0
15
0
29
8
8
0
22
15
15
22
0
0
8
% R
% Ser:
36
22
0
29
15
15
15
22
15
0
22
15
8
8
8
% S
% Thr:
8
0
0
0
22
0
8
8
8
0
0
15
0
0
0
% T
% Val:
8
0
8
8
0
0
15
0
15
0
0
0
8
15
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _